Evolutionary genomics
Curriculum vitae - Roman Hobza

Date of birth: August 23, 1976 (Valtice, Czech Republic)

Present address:
Laboratory of Plant Developmental Genetics
Institute of Biophysics, Academy of Sciences of the Czech Republic
Královopolská 135, CZ-621 65 Brno, Czech Republic
tel:+420-5-41517203 , fax:+420-5-41240500
Email: hobza@ibp.cz


Education

1994-1998 Faculty of Biology JU, České Budějovice

1998-2000 M.Sc. in Molecular Biology and Genetics, Masaryk University Brno, Czech

Republic

2004 RNDr. Masaryk University Brno, Czech Republic

2000-2004 Ph.D. in Genetics, Masaryk University Brno, Czech Republic



Professional experience:


2000- Laboratory of Plant Developmental Genetics, Institute of Biophysics, Czech Academy of Sciences, Brno, Czech Republic

2006 One-year postdoctoral fellow in the lab of Prof. Alex Widmer, Institute of Integrative Biology, ETH Zurich, Switzerland

2001 Graduate research assistant in the laboratory of Dr. Sarah Grant, Department of Biology, University of North Carolina at Chapel Hill



Professional scientific focus:

Plant genomics, microdissection of chromosomes, evolution of sex chromosomes, speciation, evolution of adaptation machanisms.


Teaching:¨

Semestral course „Genetic Engineering“ at Agricultural Faculty, MZLU in Brno


Semestral course „Evolutionary genomics“ at Faculty of Sciences, Masaryk University in Brno

Semestral course „Evolutionary genomics“ at Faculty of Sciences, University of South Bohemia in České Budějovice

Semestral course „Structure and evolution of genomes“ at Faculty of Pharmacy, University of Veterinary and Farmaceutical Sciences in Brno

Diploma and doctoral theses supervision



Principal investigator of grants:

2009-2013 Czech Science Foundation (522/09/0083) Isolation and characterization of X-chromosome linked genes in Silene latifolia

2009-2011 The Grant Agency of AS CR (KJB600040901) Establishment of Silene vulgaris as a model for comparative genomics in genus Silene

2009-2011 Internal Grant of AS CR (M200040905) Genus Silene as a model for mating system and adaptation mechanisms evolution – from ecology to genomics



Book chapters:

1. “Plant Genome – Biodiversity and Evolution”, Sharma AK and Sharma A eds, Science Publishers, New Hampshire, USA (2007): Zluvova J, Janousek B, Hobza R, Mracek J, Widmer A, Vyskot B – Genus Silene (Caryophyllaceae): Evolutionary Diversification and Sex Chromosome Formation (in press)

2. ”Floriculture, Ornamental and Plant Biotechnology: Advances and Topical Issues” (1st Edition), Teixeira da Silva JA ed, Global Science Books, London, UK (2006): Hobza R, Vyskot B: Chapter 25 - Sex Chromosomes in Plants, pp. 224-235



Selected scientific papers:


Kejnovsky E, Hobza R, Kubat Z, Cermak T & Vyskot B (2009) The role of repetitive DNA in structure and evolution of sex chromosomes in plants. Heredity (in press)


Hobza R & Widmer A (2008) Efficient molecular sexing in dioecious Silene latifolia and S. dioica and paternity analysis in F1 hybrids. Molecular Ecology Resources (in press).


Cermak T, Kubat Z, Hobza R, Koblizkova A, Widmer A, Macas J, Vyskot B & Kejnovsky E (2008) Survey of repetitive sequences in Silene latifolia with respect to their distribution on sex chromosomes. Chromosome Research 16: 961-976.


Mrackova M, Nicolas M, Hobza R, Negrutiu I, Monéger F, Widmer A, Vyskot B & Bohuslav Janousek (2008) Independent origin of sex chromosomes in two species of the genus Silene. Genetics 179: 1129-1133.


Marais G, Nicolas M , Bergero R, Chambrier P, Kejnovsky E, Monéger F, Hobza R, Widmer A & Charlesworth D (2008) Evidence for degeneration of the Y chromosome in the dioecious plant Silene latifolia. Current Biology 18: 545-549.


Kubat Z, Hobza R, Vyskot B and Eduard Kejnovsky (2008) Microsatellite accumulation on the Y chromosome in Silene latifolia. Genome (in press).


Hobza R, Kejnovsky E, Vyskot B, Widmer A (2007) The role of chromosomal rearrangements in the evolution of Silene latifolia sex chromosomes. Molecular Genetics and Genomics 278: 633-638.

Yu Q, Shaobin H, Hobza R, Feltus FA, Wang X et al. (2007) Chromosomal location and gene paucity of the male specific region on papaya Y chromosome. Molecular Genetics and Genomics 278: 177-185.


Kejnovsky E, Hobza R, Kubat Z, Widmer A, Marais GA & Vyskot B (2007) High intrachromosomal similarity of retrotransposon long terminal repeats: Evidence for homogenization by gene conversion on plant sex chromosomes? Gene 390: 92-97. IF 2.721


Hobza R & Vyskot B (2007) Laser microdissection-based analysis of heteromorphic sex chromosomes. Methods in Cell Biology 82: 433-453. IF 1.582


Hobza R, Hrusakova P, Safar J, Bartos J, Janousek B, Zluvova J, Michu E, Dolezel J & Vyskot B (2006) MK17, a specific marker closely linked to the gynoecium suppression region on the Y chromosome in Silene latifolia. Theoretical and Applied Genetics 113: 280-287.

Hobza R, Lengerova M, Svoboda J, Kubekova H, Kejnovsky E & Vyskot B (2006) An accumulation of tandem DNA repeats on the Y chromosome in Silene latifolia during early stages of sex chromosome evolution. Chromosoma 115: 376-382.


Kejnovsky E, Kubat Z, Macas J, Hobza R, Mracek J, Vyskot B (2006) Retand: A novel family of gypsy-like retrotransposons harboring an amplified tandem repeat. Molecular Genetics and Genomics 276: 254-263.


Kejnovsky E, Kubat Z, Hobza R, Lengerova M, Sato I, Tabata S, Fukui K, Matsunaga S & Vyskot B (2006) Accumulation of chloroplast DNA sequences on the Y chromosome of Silene latifolia. Genetica 128: 167-175.


Zluvova J, Lengerova M, Markova M, Hobza R, Nicolas M, Vyskot B, Charlesworth D, Negrutiu I & Janousek B (2005) The inter-specific hybrid Silene latifolia x S. viscosa reveals early events of sex chromosome evolution. Evolution and Development 7: 327-336.


Vyskot B & Hobza R (2004) Gender in plants: sex chromosomes are emerging from the fog. Trends in Genetics 20: 432-438.


Hobza R, Lengerova M, Cernohorska H, Rubes J & Vyskot B (2004) FAST-FISH with laser beam microdissected DOP-PCR probe distinguishes the sex chromosomes of Silene latifolia. Chromosome Research 12: 245-250.


Lengerova M, Kejnovsky E, Hobza R, Macas J, Grant SR & Vyskot B (2004) Multicolor FISH mapping of the dioecious model plant, Silene latifolia. Theoretical and Applied Genetics 108: 1193-1199. IF 2.715